The oxygen sensitivity of hamster cheek pouch arterioles. In vitro and in situ studies.
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چکیده
منابع مشابه
The oxygen sensitivity of hamster cheek pouch arterioles. In vitro and in situ studies.
We tested the hypothesis that a parenchymally derived mediator is required for arterioles to exhibit oxygen sensitivity. To that end, the parenchyma was dissected and removed from around hamster cheek pouch arterioles, and the oxygen sensitivity of these "aparenchymal arteriolar segments" was studied, either in vitro, after cannulation, or in situ. Arteriolar segments in situ with and without p...
متن کاملCapillaries and arterioles are electrically coupled in hamster cheek pouch.
In this report we demonstrate electrical communication in the microcirculation between arterioles and capillary networks in situ. Microvessel networks in the hamster cheek pouch, which included capillaries and their feeding arterioles, were labeled with the voltage-sensitive dye di-8-ANEPPS by intraluminal perfusion through a micropipette. Pulses of 140 mM potassium solution were applied by pre...
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The responses to changes in transmural pressure were investigated in pulmonary allograft and cheek pouch arterioles in two oxygen environments. Neonatal hamster lung tissue was transplanted into adult hamster cheek pouches. After vascularization (8-10 days), pulmonary and cheek pouch vessels were observed by intravital microscopy in hamsters anesthetized with pentobarbital. By gassing the suffu...
متن کاملCarcinogenesis in the Hamster Cheek Pouch
Pouches from three experimental and one control animal were excised for analysis at various times during the first week and thereafter each week of carcinogen application (9,10-dimethyl-l ,~-benzanthracene) until the 131h week, at which time large tumors were present in all remaining aninmls. IIistologic progression from normal through inflanmmtion, uniform hyperplasia, localized premalignant h...
متن کاملMicrovascular pressure distribution and responses of pulmonary allografts and cheek pouch arterioles in the hamster to oxygen.
Despite extensive investigations of the pulmonary circulation using both in vitro and in vitro preparations, few direct microcirculatory studies have been made. Consequently, the mechanisms involved in the response of the pulmonary microvasculature to changes in oxygen tension remain unclear. The present study represents the first direct observation of the responses in pulmonary microvessels to...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1983
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.53.4.515